Histopathology Atlas

LYMPH NODE

WHO Classification 2016

• Histology:

  • Lymph node

• Inflammatory disorders:

  • Reactive lymph node

  • Tuberculosis

  • Castleman's disease

  • Sarcoidosis

  • Cat-scratch disease

  • Toxoplasmosis

  • Intestinal lymph node in Crohn's disease

• Neoplasms:

  • Hodgkin Lymphoma:

    • Classic

    • Lymphocyte depleted - LD

    • Lymphocyte rich classical - LR

    • Mixed cellularity - MC

    • Nodular sclerosis - NS

    • Hodgkin cells

  • B-cell lymphomas:

    • CLL/SLL

    • Follicular Lymphoma

    • Diffuse Large B-cell Lymphoma

    • Burkitt Lymphoma

    • Plasmablastic Lymphoma

  • T-cell lymphomas:

    • T-ALL

• Metastases:

  • Squamous cell carcinoma metastasis to lymph node

  • Adenocarcinoma metastasis to lymph node

  • Rhabdomyosarcoma metastasis to lymph node

  • Melanoma metastasis to lymph node

  • Thyroid papillary carcinoma metastasis to lymph node

  • Hepatocellular carcinoma metastasis to lymph node

  • Signet ring cell carcinoma metastasis to lymph node

  • Neuroblastoma metastasis to lymph node

  • Urothelial carcinoma metastasis to lymph node

SPLEEN

• Histology:

  • Spleen

• Non-neoplastic disorders:

  • Hereditary spherocytosis

  • Epithelial cyst

• Neoplasms:

  • Cavernous hemangioma

  • Lymphangioma

  • Hemangioendothelioma

THYMUS

• Histology:

  • Thymus

• Neoplasms:

  • Thymoma

  • Mediastinal (thymic) large B cell lymphoma

• Non-neoplastic disorders:

  • Thymic cyst